Scientists from Scripps Research and Los Alamos National Laboratory have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules that help shield HIV from the immune system.
Molecular & Computational biology
Oct 23, 2020
0
203
Scripps Research chemist Matthew Disney, Ph.D., and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from ...
Cell & Microbiology
Sep 30, 2020
0
209
Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants.
Biochemistry
Aug 13, 2020
0
179
Scripps Research chemists Hans Renata, Ph.D., and Alexander Adibekian, Ph.D., have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as ...
Biochemistry
Aug 6, 2020
0
2982
In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. Their study, involving the roundworm C. elegans, ...
Cell & Microbiology
Feb 25, 2020
0
203
In a study with implications for the future of drug discovery, Scripps Research scientists showed they were able to turn simple chemicals into unique 3-D structures resembling those found in nature—structures with desirable ...
Materials Science
Feb 10, 2020
0
215
A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes—the complex and evolutionarily ancient "molecular machines" that make proteins in cells ...
Cell & Microbiology
Nov 22, 2019
0
3733
Chemists at Scripps Research have invented an efficient method for making a synthetic version of the plant compound bilobalide, which is naturally produced by gingko trees. It's a significant feat because bilobalide—and ...
Biochemistry
Oct 17, 2019
1
87
To truly understand how the body works and improve human health, researchers need to tease apart the building blocks of our cells. But as scientists continue to make major breakthroughs in cellular biology, an important question ...
Biochemistry
Oct 9, 2019
0
199
A new chemistry method from scientists at Scripps Research in La Jolla, California, greatly simplifies the creation of an important class of compounds called hindered ethers, which are integral to many drugs and commercial ...
Materials Science
Sep 9, 2019
1
93
