A team of researchers from the Chinese Academy of Sciences, Tsinghua University and Peking University has determined the holoenzyme structure of monkeypox DNA using cryo-electron microscopy. In their paper published in the ...
A defense mechanism that human cells possess against viruses such as monkeypox, herpes simplex and human papillomavirus—all double-stranded DNA viruses—relies on proteins that patrol the cell, acting as sensors of the ...
Biotechnology
Nov 29, 2022
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39
Viral DNA in human genomes, embedded there from ancient infections, serves as antivirals that protect human cells against certain present-day viruses, according to new research.
Molecular & Computational biology
Oct 27, 2022
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300
Scientists at EPFL have determined how a protein that is critical in our first line of immune defense is regulated in the cell to prevent autoinflammatory diseases.
Cell & Microbiology
Oct 25, 2022
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33
A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC San Francisco (UCSF), ...
Biotechnology
Aug 25, 2022
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83
The human immune system is a complex network of organs, cells and proteins that defend the body against infections and diseases. While our bodies work constantly to ensure invading infections don't breach the defenses, viruses ...
Cell & Microbiology
Aug 24, 2022
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260
Bacteria use a variety of defense strategies to fight off viral infection, and some of these systems have led to groundbreaking technologies, such as CRISPR-based gene-editing. Scientists predict there are many more antiviral ...
Cell & Microbiology
Aug 11, 2022
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137
An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how ...
Cell & Microbiology
Jul 18, 2022
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33
Cyclic GMP-AMP synthase (cGAS), a double-stranded DNA (dsDNA) sensing protein, plays an important role in the strong innate immune response induced by pathogen derived nucleic acids.
Molecular & Computational biology
May 12, 2022
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12
Like most organisms, bacteria are preyed upon by viruses—and their go-to approach to destroying the invaders is to simply chop them up. As soon as it sees a virus, a bacterium may employ a host of immune strategies to slice ...
Molecular & Computational biology
Mar 25, 2022
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506
