Researchers on the Broad Institute's Cancer Dependency Map (DepMap) team have released DEMETER2, an upgraded version of an open source software tool that identifies cancer cells' genetic dependencies (genes they need in order ...
Biotechnology
Nov 6, 2018
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27
Insects and plants have an important ancient defence mechanism that helps them to fight viruses. This is encoded in their DNA. Scientists have long assumed that vertebrates - including humans - also had this same mechanism. ...
Cell & Microbiology
Sep 15, 2017
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22
Continuously throughout our lives, our cells are expressing genes. It's the first step in making proteins, the stuff of all the structures in the body and molecular players in the countless dramas unfolding every second as ...
Cell & Microbiology
Aug 3, 2017
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140
Some cells just don't get the respect they deserve. In fact, most cells don't. Over 99 percent of the innumerable cells on our planet exist in a state of quiescence. Pick up a handful of soil: it contains thousands of microorganisms, ...
Cell & Microbiology
Nov 9, 2016
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299
Anaplastic thyroid cancer (ATC), the most aggressive form of thyroid cancer, has a mortality rate of nearly 100 percent and a median survival time of three to five months. One promising strategy for the treatment of these ...
Bio & Medicine
Jun 20, 2016
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354
Scientists at Cold Spring Harbor Laboratory (CSHL) have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi.
Cell & Microbiology
Dec 5, 2014
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0
Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery—it is extremely ...
Biotechnology
Nov 17, 2014
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0
Biologists have long wondered if mammals share the elegant system used by insects, bacteria and other invertebrates to defend against viral infection. Two back-to-back studies in the journal Science last year said the answer ...
Cell & Microbiology
Jun 23, 2014
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0
(Phys.org) —A new technique to fight crop insect pests may affect different insect populations differently, researchers report. They analyzed RNA interference (RNAi), a method that uses genetic material to "silence" specific ...
Ecology
Mar 11, 2014
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0
The team of Johannes Zuber at the IMP in Vienna, Austria, managed to overcome remaining key limitations of RNA interference (RNAi) - a unique method to specifically shut off genes. By using an optimized design, the scientists ...
Cell & Microbiology
Dec 13, 2013
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