A team of engineers at Duke University have developed a method to broaden the reach of CRISPR technologies. While the original CRISPR system could only target 12.5% of the human genome, the new method expands access to nearly ...
Biotechnology
Dec 5, 2023
0
428
Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains.
Cell & Microbiology
Nov 8, 2023
0
19
The human genome, from end to end, has been sequenced, meaning scientists worldwide have identified most of the nearly 20,000 protein-coding genes. However, an international group of scientists notes there's more work to ...
Molecular & Computational biology
Oct 13, 2023
0
103
New work by scientists in the U.S. and China shows how a fertilized egg cell, or zygote, hits "reset" so that the newly formed embryo can develop according to its own genetic program. The study was published July 17 in Nature.
Cell & Microbiology
Jul 20, 2023
0
34
CRISPR gene editing is a breakthrough that has been used to treat diseases such as sickle cell anemia, leukemia and genetic disorders, but it has challenges that limit its broad utility.
Biotechnology
Jun 29, 2023
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15
Systematically attenuating DNA targeting activity can achieve CRISPR-driven editing in bacteria, greatly boosting colony counts and even increasing the frequency of precise genome editing. This was shown in a study of the ...
Cell & Microbiology
Feb 9, 2023
0
69
On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein. This process, known as alternative splicing, allows a single gene to ...
Molecular & Computational biology
Jan 20, 2023
1
168
Genetic information encoded in genomic DNA is transcribed to mRNAs and then the codons on mRNA are decoded by transfer RNAs (tRNAs) during protein synthesis. tRNAs deliver amino acids to ribosomes and proteins are synthesized ...
Biochemistry
Dec 27, 2022
0
68
The body needs a lot of blood. In humans, 200 billion new erythrocytes—or red blood cells—are generated daily by erythropoiesis, a multi-step process starting from blood-related stem cells, requiring rigorous maintenance ...
Cell & Microbiology
Nov 29, 2022
0
26
The human genome has just over 20,000 genes coding for proteins. Yet, it produces at least ten times that many different non-coding RNA molecules, which can often take on more than one shape. At least some of this RNA structurome ...
Cell & Microbiology
Nov 9, 2022
0
27
