DNA repair enzyme mapped in atomic detail

An enzyme crucial to the process of DNA repair in our cells has been mapped in atomic detail by researchers at the University of Dundee, the UK's top-rated University for Biological Sciences.

New class of DNA repair enzyme discovered

This year's Nobel Prize in chemistry was given to three scientists who each focused on one piece of the DNA repair puzzle. Now a new study, reported online Oct. 28 in the journal Nature, reports the discovery of a new class ...

Cells repair damaged DNA by a different mechanism than assumed

Defects in DNA can cause serious harm to an organism, including cell death or the development of cancer. Efficient repair mechanisms are therefore of vital importance. LMU chemist Professor Christian Ochsenfeld, Chair of ...

How bacterial cell recognizes its own DNA

It may come as a bit of a surprise to learn that bacteria have an immune system - in their case to fight off invasive viruses called phages. And like any immune system - from single-celled to human - the first challenge of ...

Untying DNA knots

Structural biologists at the Friedrich Miescher Institute for Biomedical Research have resolved the 3D structure of a protein machine that plays an important part in the maintenance of genomic stability. They have revealed ...

New calculations solve an old problem with DNA

The normal (B-form) DNA will switch to left-handed DNA when it is physically twisted, or when a lot of salt is added to the solution. Researchers at the University of Luxembourg were able to accurately calculate for the ...

A question of gene silencing

When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...

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