Sperm meets egg, setting off a cascade of events leading to the creation of an embryo. But how do developing cells—which all contain the same genetic information—decide what to be when they grow up? How does a cell differentiate ...
Cell & Microbiology
May 10, 2022
0
49
Primordial germ cells (PGCs) are the first germ-cell population established during development. The survival of species is dependent upon PGCs in sexually reproducing organisms because they are the founder cells for the germline.
Cell & Microbiology
May 10, 2022
0
58
To prevent the extinction of the northern white rhino, the international consortium BioRescue is attempting to create artificial egg cells from stem cells. A team led by MDC's Sebastian Diecke and Micha Drukker of Leiden ...
Ecology
Mar 10, 2022
2
503
Researchers have shown for the first time that embryonic cells destined to become either egg or sperm rely on different methods of repressive gene regulation.
Cell & Microbiology
Dec 9, 2021
0
39
Fruit flies (Drosophila) are important model organisms for biological research. Molecular tools exist that can turn on (or induce) gene expression in fruit flies, allowing researchers to learn more about the functions of ...
Plants & Animals
Nov 26, 2021
0
256
The fruit fly Drosophila melanogaster has long been an important experimental model for biological research. While you may be eager to rid your kitchen of this unwanted pest, researchers in Japan have developed a new technique ...
Molecular & Computational biology
Oct 13, 2021
0
5
Whenever an organism develops and forms organs, a tumor creates metastases or the immune system becomes active in inflammation, cells migrate within the body. As they do, they interact with surrounding tissues which influence ...
Cell & Microbiology
Jan 7, 2021
1
46
A team led by UT Southwestern has derived a new "intermediate" embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.
Cell & Microbiology
Dec 3, 2020
0
218
In most cases, taking a break isn't the most efficient way of getting a job done. But in a study published this week in iScience, researchers from Japan's University of Tsukuba have uncovered the regulatory pathway governing ...
Cell & Microbiology
Mar 23, 2020
0
5
Early in mammalian embryonic development, long before the organism's ultimate form has taken shape, a precious subset of its cells are set aside for future use in creating offspring. This task bestows on that subset of cells ...
Molecular & Computational biology
Nov 22, 2019
0
70
