After five years of experimentation, researchers from the University of Copenhagen have succeeded in crystallising and mapping a novel conformation of LeuT, a bacterial protein that belongs to the same family of proteins ...
Biochemistry
Mar 6, 2020
0
925
The structure of a transport complex used by bacteria to import aspartate has been mapped in unique detail by University of Groningen scientists. The proteins were imaged using cryo-electron microscopy. The results reveal ...
Cell & Microbiology
Feb 24, 2020
0
28
Neurochemicals such as serotonin and dopamine play crucial roles in cognitive and emotional functions of our brain. Vesicular monoamine transporter 1 (VMAT1) is one of the genes responsible for transporting neurotransmitters ...
Evolution
Dec 23, 2019
0
28
Dopamine, serotonin, adrenalin... The smooth functioning of the human brain depends on their correct proportions. Any disturbances mean diseases. That's why it's so important to be able to detect these disturbances as early ...
Analytical Chemistry
Oct 23, 2019
0
9
The research team led by Dr. Daisuke Ono and Prof. Akihiro Yamanaka of the Graduate School of Medicine, Nagoya University, along with collaborators, has revealed that inhibitory neurons (GABAergic neurons) of the central ...
Plants & Animals
Aug 28, 2019
0
12
Many biomolecules come in two versions that are each other's mirror image, like a left and a right hand. Cells generally use the left-hand version of amino acids to produce proteins, and uptake mechanisms were thought to ...
Biochemistry
Apr 26, 2019
0
70
Researchers at the University of Twente have designed a tiny needle in which micro-channels can be used for extracting small liquid samples from a local area of the brain. The needle is about as thick as a human hair. Thanks ...
Analytical Chemistry
Mar 14, 2019
0
9
UC San Francisco researchers have for the first time developed a strategy for targeting a key molecule implicated in Parkinson's disease, opening up a potential new treatment strategy for the currently incurable movement ...
Biochemistry
Mar 7, 2019
0
326
Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualised serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely ...
Biochemistry
Feb 14, 2019
0
5
Somatic stem cells are microscopic workhorses, constantly regenerating cells throughout the body: skin and the lining of the intestine, for example. And to University of Illinois neuroscientists, they represent untapped potential.
Cell & Microbiology
Oct 17, 2018
4
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