Researchers reveal new molecular mechanism for Parkinson's disease risk
In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
Cell & Microbiology
Jun 23, 2022
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29
A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.
Cell & Microbiology
May 19, 2022
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43
Plant colonization by biotrophic pathogens requires sophisticated strategies for tissue invasion, defense suppression and metabolic manipulation to loot nutrients necessary for their growth and reproduction. The biotrophic ...
Molecular & Computational biology
May 5, 2022
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15
Although it is widely used in the food, cosmetic, and pharmaceutical industries worldwide, the breakdown of carminic acid (a natural red dye extracted from insects) in nature has remained unclear. Through a combination of ...
Cell & Microbiology
Oct 5, 2021
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20
PON1 (paraoxonase 1), an enzyme associated with high-density lipoprotein (HDL), breaks down lipid peroxides, highly reactive fatty molecules that can damage blood vessels.
Biochemistry
Aug 20, 2021
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288
The unicellular green alga Chlamydomonas reinhardtii has already given research a massive boost: One of its light sensors, channelrhodopsin-2, founded the success of optogenetics about 20 years ago.
Biotechnology
Mar 29, 2021
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10
Researchers at the UAB have designed minimalist biostructures that imitate natural enzymes, capable of carrying out two differentiated and reversibly regulated activities thanks to a unique combination of structural and functional ...
Bio & Medicine
Mar 8, 2021
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125
An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system in recognizing and repairing DNA that has been damaged by ultraviolet (UV) light. The investigators at Kobe University ...
Molecular & Computational biology
Dec 8, 2020
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8
A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.
Biochemistry
Oct 22, 2020
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9
Noonan syndrome (NS) and Noonan syndrome with multiple lentigines (NS-ML) are rare human developmental disorders caused by mutations of the protein SHP2. Until recently, the mechanism of NS and NS-ML pathogenesis had been ...
Molecular & Computational biology
Oct 1, 2020
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8