How TFIIH uses XPG to located damaged DNA
Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.
Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.
Cell & Microbiology
Dec 8, 2022
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71
Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents. Dysfunction in this pathway ...
Cell & Microbiology
Sep 27, 2022
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95
A simple statistical test shows that contrary to current practice, the "gaps" within DNA protein and sequence alignments commonly used in evolutionary biology can provide important information about nucleotide and amino acid ...
Evolution
Aug 16, 2022
3
591
For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial ...
Biotechnology
Jul 8, 2022
1
157
Nitriles, a class of organic molecules with a cyano group—that is, a carbon atom bound with a triple unsaturated bond to a nitrogen atom—are typically toxic. But paradoxically, they are also a key precursor for molecules ...
Astronomy
Jul 8, 2022
1
641
When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.
Cell & Microbiology
May 9, 2022
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368
Two studies provide a radically new picture of how bacterial cells continually repair damaged sections (lesions) in their DNA.
Molecular & Computational biology
Mar 30, 2022
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32
Imagine Bach's "Cello Suite No. 1" played on a strand of DNA.
Bio & Medicine
Mar 3, 2022
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327
An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira ...
Biochemistry
May 18, 2021
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7
An international team of researchers led by computer scientists at the University of California San Diego have identified 163 variable number tandem repeats (VNTRs) that actively regulate gene expression. In a paper published ...
Biotechnology
Apr 12, 2021
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20