A refined approach to proteins at low resolution

Membrane proteins and large protein complexes are notoriously difficult to study with X-ray crystallography, not least because they are often very difficult, if not impossible, to crystallize, but also because their very ...

Probing for biological polymorphs

(Phys.org) —Humans have devised many amazing and versatile materials (such as plastic and steel) that do not exist in nature. On the other hand, nature has created structures and substances that materials scientists and ...

Tiny crystals could revolutionize structural biology studies

For structural biologists, the first step in determining a protein's precise molecular structure is often the hardest: coaxing the protein to grow into the orderly, three-dimensional crystals that are the starting material ...

First-ever determination of protein structure with X-ray laser

(Phys.org) —An international team of researchers, including LLNL physicist Matthias Frank and postdoc Mark Hunter, have for the first time used an ultra-intense X-ray laser to determine the previously unknown atomic-scale ...

Anti-flu proteins work as designed, researchers confirm

(Phys.org)—Understanding why proteins interact with certain specific molecules and not with the myriad others in their environment is a major goal of molecular biology. Now, in a series of recent papers, researchers describe ...

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