The 'weakest link' in the aging proteome

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are ...

Using computational biology for the annotation of proteins

Research carried out at Universidad Carlos III of Madrid in collaboration with the Centro Nacional de Investigaciones Oncologicas employed computational techniques to improve the characterization of proteins. The system they ...

Cellular metabolism self-adapts to protect against free radicals

Oxygen-consuming organisms obtain energy through cellular respiration, which is the transformation of carbohydrates and oxygen into carbon dioxide and water. This process also produces toxic oxygen radicals which must be ...

Recycling fat might help worms live longer

Aging is generally accepted as a universal fact of life, but how do humans and other organisms age at the molecular level? At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team led by Malene Hansen, Ph.D., ...

Common weed could provide clues on aging and cancer

A common weed and human cancer cells could provide some very uncommon details about DNA structure and its relationship with telomeres and how they affect cellular aging and cancer, according to a team led by scientists from ...

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