Researchers from the Bhogaraju Group at EMBL Grenoble have gained new insights into how a cancer-relevant family of proteins bind their targets. The results of the study, published in The EMBO Journal, could potentially help ...
Molecular & Computational biology
Mar 6, 2024
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Boston College researchers used a mild charge of electricity to precisely modify proteins, a new tool that can be used to develop novel biotherapeutics and protein-based research tools, the team reported recently in the journal ...
Biochemistry
Mar 5, 2024
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99
New research from the Weeks Lab in the Department of Biochemistry opens the door for scientists to explore cell death, a critical biochemical process, with greater ease.
Cell & Microbiology
Feb 20, 2024
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45
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. ...
Cell & Microbiology
Feb 5, 2024
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73
Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...
Biochemistry
Jan 30, 2024
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8
St. Jude Children's Research Hospital scientists have published their work on SJ3149, a compound with broad activity against many cancer types, particularly acute myeloid leukemia (AML). SJ3149 sticks to the cancer-related ...
Biochemistry
Jan 16, 2024
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61
The cells in our bodies constantly divide and renew themselves. But if division goes wrong, cancer or other diseases can result. Now, University of Connecticut researchers have profiled two elusive proteins critical for healthy ...
Cell & Microbiology
Jan 11, 2024
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1
Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs.
Molecular & Computational biology
Jan 8, 2024
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4
Disease-causing bacteria of the genus Salmonella or Yersinia can use tiny injection apparatuses to inject harmful proteins into host cells, much to the discomfort of the infected person. However, it is not only with a view ...
Cell & Microbiology
Jan 3, 2024
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68
Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound ...
Cell & Microbiology
Dec 13, 2023
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