One of the hallmark traits of Alzheimer's disease, a debilitating disorder marked by memory deficits and general cognitive decline, is the accumulation in the brain of a protein called b-amyloid. These proteins form "plaques" ...
Biochemistry
Oct 23, 2018
0
689
Small interfering RNA sounds like something from a science fiction novel rather than a revolutionary type of medicine. But this odd-sounding new drug offers a novel strategy for treating disease by targeting the root cause ...
Biotechnology
Aug 17, 2018
0
7
Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain. They may pave the way for better diagnosis of neurodegenerative ...
Biochemistry
Dec 21, 2017
0
18
Like millions of Americans, Harvard Medical School postdoctoral fellow Tom Seegar struggled as he watched several family members decline from Alzheimer's disease.
Cell & Microbiology
Dec 12, 2017
0
33
After a flu virus infects a host cell and hijacks its inner workings to create copies of itself, these copies gather into viral buds that break free from the host cell to infect again. A new study from MIT now provides the ...
Biochemistry
Nov 20, 2017
0
8
An international team of researchers have discovered a new type of transition in protein folding: amyloid crystals formed from amyloid fibrils by a decrease in energy. The crystals are even more stable than the fibrils, which ...
Biochemistry
Nov 7, 2017
0
12
A team of researchers from Germany and the Netherlands has determined the structure of an amyloid fibril with previously unachieved resolution. The fibrils of the body's own amyloid beta (Aβ) protein are the main constituent ...
Biochemistry
Sep 8, 2017
0
744
A team of scientists from the VIB lab of Han Remaut (VIB-VUB) and the lab of Yves Dufrêne at UCL Louvain-La-Neuve collaborated on a study of functional amyloids –protein aggregates with the typical amyloid structure that ...
Biochemistry
Jun 20, 2017
0
3
In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the ...
Bio & Medicine
Jan 17, 2017
0
829
Scientists at The Scripps Research Institute (TSRI) have developed a broadly useful method to unmask new functional features of human proteins.
Biochemistry
Nov 1, 2016
0
185
