A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's. An international team of researchers ...
General Physics
May 9, 2018
0
21
An international team of researchers have discovered a new type of transition in protein folding: amyloid crystals formed from amyloid fibrils by a decrease in energy. The crystals are even more stable than the fibrils, which ...
Biochemistry
Nov 7, 2017
0
12
A team of researchers from Germany and the Netherlands has determined the structure of an amyloid fibril with previously unachieved resolution. The fibrils of the body's own amyloid beta (Aβ) protein are the main constituent ...
Biochemistry
Sep 8, 2017
0
744
Cambridge researchers have identified - and shown that it may be possible to control - the mechanism that leads to the rapid build-up of the disease-causing 'plaques' that are characteristic of Alzheimer's disease.
General Physics
Jul 18, 2016
0
112
A metallic molecule being studied at Rice University begins to glow when bound to amyloid protein fibrils of the sort implicated in Alzheimer's disease. When triggered with ultraviolet light, the molecule glows much brighter, ...
Biochemistry
Jul 7, 2016
0
12
Formation of amyloid fibrils is a characteristic feature of neurogenerative diseases like Alzheimer's. As published in the journal Angewandte Chemie, German and American scientists have found evidence that these fibrils adopt ...
Biochemistry
Mar 15, 2016
0
10
Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVs. Even for scientists, it has not been easy to find other ways of using them.
Materials Science
Sep 23, 2015
0
46
Researchers from FOM Institute AMOLF have, for the first time ever, managed to make an image of the exterior structure of a protein aggregate that causes diseases like Alzheimer and type-2 diabetes. They discovered that the ...
Bio & Medicine
May 8, 2015
0
615
Nature has many examples of self-assembly, and bioengineers are interested in copying or manipulating these systems to create useful new materials or devices. Amyloid proteins, for example, can self-assemble into the tangled ...
Bio & Medicine
Jan 26, 2015
0
728
Ebola virus, Alzheimer's amyloid fibrils, tissue collagen scaffolds and cellular cytoskeleton are all filamentous structures that spontaneously assemble from individual proteins.
Bio & Medicine
Jan 5, 2015
0
23
