Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
0
34
In the battle against cancer and other diseases, scientists are developing molecular weapons that can be used to stop uncontrollable cell growth.
Biochemistry
Apr 3, 2024
0
1
A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.
Biochemistry
Feb 21, 2024
0
16
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
0
66
By using single-antibodies, Professor Hirohide Saito (Department of Life Science Frontiers) and his team of researchers, Shodai Komatsu and Assistant Professor Hirohisa Ohno, have developed a novel system to control gene ...
Biotechnology
Nov 20, 2023
0
18
One double-helix strand of DNA could extend six feet, but it is so tightly coiled that it packs an entire sequence of nucleotides into the tiny nucleus of a cell. If that same DNA was instead split into two strands and divided ...
Biotechnology
Oct 17, 2023
0
85
The sex hormone commonly known as estrogen plays an important role in multiple aspects of women's health and fertility. High levels of estrogen in the body are associated with breast and ovarian cancers, while low levels ...
Bio & Medicine
Sep 28, 2023
1
21
Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers from the University of Eastern Finland teamed up with industry and supercomputers ...
Analytical Chemistry
Sep 22, 2023
0
18
Discovering and developing drugs can be slow, costly and high-risk, but harnessing advances in artificial intelligence (AI) can help with these processes, say Brock University researchers.
Molecular & Computational biology
Aug 1, 2023
0
30
Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.
Biotechnology
Jul 21, 2023
0
76
