Study reveals ways in which cells feel their surroundings
Jul 18, 2017
Cells push out tiny feelers to probe their physical surroundings, but how much can these tiny sensors really discover? A new study led by Princeton University researchers and colleagues finds that the typical cell's environment ...
Biosensors light up cellular signaling processes
Jul 17, 2017
Researchers at the University of California, Riverside have converted a naturally occurring fluorescent protein from corals into a biosensor that can be used to monitor the cellular thioredoxin (Trx) system, which is a promising ...
Big-data analysis points toward new drug discovery method
Jul 12, 2017
A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been ...
'Nanolock' detects cancer mutation; could lead to early diagnoses, personalized therapies
Jul 05, 2017
The moment when healthy cells turn into cancer cells is a critical point. And if caught early enough, many cancers can be stopped in their tracks. One group reports in ACS Sensors that they have developed an accurate and ...
New insight into how telomeres protect cells from premature senescence
Jun 30, 2017
Researchers at the Institute of Molecular Biology (IMB) and Johannes Gutenberg University Mainz (JGU) have further uncovered the secrets of telomeres, the caps that protect the ends of our chromosomes. They discovered that ...
Colon cancer nuclear pore dynamics are captured by HS-AFM
Jun 30, 2017
One of the key reasons for cancer mortality is the highly invasive behaviour of cancer cells, which is often due to aggressive metastasis. Metastasis is facilitated by various growth factors and cytokines secreted from cells ...
A new ribosomal biogenesis regulation point to treat cancer and 5q- syndrome
Jun 29, 2017
Researchers at the Catalan Institute of Oncology have discovered a new role for free 40S ribosomes as guardians of genetic information required to synthesize themselves. This mechanism, which relies on a complex of free 40S ...
Micron-sized hydrogel cubes show highly efficient delivery of a potent anti-cancer drug
Jun 28, 2017
Many potent anti-cancer drugs have major drawbacks—they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.
Glycans as biomarkers for cancer?
Jun 26, 2017
Glycosylated proteins are often overexpressed in tumor cells and thus could serve as tumor markers, especially those with the interesting molecule sialic acid as their sugar moiety. In the journal Angewandte Chemie, American ...
Using 'sticky' nanoparticles, researchers develop strategy to boost body's cancer defenses
Jun 26, 2017
After radiation treatment, dying cancer cells spit out mutated proteins into the body. Scientists now know that the immune system can detect these proteins and kill cancer in other parts of the body using these protein markers ...