Van Andel Institute (VAI) is a 501(c)(3) nonprofit organization in Grand Rapids, Michigan. The Institute’s mission is to improve the health and enhance the lives of current and future generations through disease research and science education. VAI was founded by Jay and Betty Van Andel in 1996 and is composed of two complementary institutes: Van Andel Research Institute (VARI) and Van Andel Education Institute (VAEI). VARI scientists study the genetic, cellular, and molecular origins of cancer and other diseases and work to translate those findings into effective therapies for patients. VAEI provides a continuum of learning through a variety of educational programs that help to prepare tomorrow’s scientists.
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Van Andel Institute scientists have developed a new extraction protocol for RNA-seq and metabolomic analysis, offering a more complete picture of cellular activity than either technique on its own.
Molecular & Computational biology
May 2, 2023
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8
An enzyme that combats the greenhouse gas nitrous oxide (N2O) may one day give scientists a potent new tool for reducing the amount of the gas in the atmosphere thanks in part to new findings published today in Nature.
Materials Science
Jul 27, 2022
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28
A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and disease in a vital model organism.
Biotechnology
Jul 13, 2022
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15
Plants rely on their ability to sense light for survival. But unlike animals, plants don't have eyes full of photoreceptors to capture and convey messages from visual stimuli. Instead, plants are coated with a network of ...
Plants & Animals
Mar 30, 2022
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43
When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.
Cell & Microbiology
Mar 21, 2022
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35
The same taste-sensing molecule that helps you enjoy a meal from your favorite restaurant may one day lead to improved ways to treat diabetes and other metabolic and immune diseases.
Cell & Microbiology
Jun 24, 2021
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21
For more than a decade, scientists studying epigenetics have used a powerful method called ChIP-seq to map changes in proteins and other critical regulatory factors across the genome. While ChIP-seq provides invaluable insights ...
Biochemistry
Nov 20, 2020
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129
For the first time, scientists have visualized a new class of molecular gates that maintain pH balance within brain cells, a critical function that keeps cells alive and helps prevent stroke and other brain injuries.
Cell & Microbiology
Nov 4, 2020
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747
Van Andel Institute scientists have for the first time described the near-atomic level structure of a molecular pathway that plays critical roles in human development, blood pressure regulation, inflammation and cell death. ...
Biotechnology
Jun 3, 2020
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168
Van Andel Institute scientists have revealed the first known atomic structure of a "molecular machine" responsible for installing critical signaling proteins into cellular membranes.
Molecular & Computational biology
Jun 3, 2020
0
21
