Structure of key DNA replication protein solved

A research team led by scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself. Investigators say that knowing ...

Researchers develop tool to determine function of MicroRNAs

As microRNA biology has been implicated in everything from the development of cancer to virus infections, a new tool developed by scientists at the Icahn School of Medicine at Mount Sinai holds tremendous potential to develop ...

Factor found to balance medically useful stem cell qualities

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

Mammals defend against viruses differently than invertebrates

Biologists have long wondered if mammals share the elegant system used by insects, bacteria and other invertebrates to defend against viral infection. Two back-to-back studies in the journal Science last year said the answer ...

Stem cells are wired for cooperation, down to the DNA

We often think of human cells as tiny computers that perform assigned tasks, where disease is a result of a malfunction. But in the current issue of Science, researchers at The Mount Sinai Medical Center offer a radical view ...

New technology transforms research in viral biology

Researchers at The Mount Sinai Medical Center have developed an innovative system to test how a virus interacts with cells in the body—to see, for example, what happens in lung cells when a deadly respiratory virus attacks ...

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