New method boosts the study of regulation of gene activity

One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off. Methyl groups are one of these chemical modifications or tags. ...

A molecular glue for turning on human cell pluripotency

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types in an organism. Pluripotent ...

Team develops quality control for single cell imaging

One size doesn't necessarily fit all when it comes to testing the effects, including cancer and other diseases, of endocrine-disrupting chemicals (EDC) or toxins, which target many factors, including the estrogen receptor ...

SRC-3 is a key regulator of the 12-hour clock

Many people have heard of the circadian rhythms or biological processes that follow a 24-hour cycle. Sleeping at night and being awake during the day is a well-known example of a circadian rhythm. Less well known are the ...

Dynamic twists and loops can enable DNA to modulate its function

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every ...

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