Intrinsically disordered proteins (IDPs) are widely found in the proteomes of eukaryotes and play key roles in life processes such as transcription of genetic information and signaling. Apart from being usually highly repetitive, ...
Biochemistry
Jan 15, 2024
0
18
A research group at Nagoya University in Japan has developed a new catalyst that promises to revolutionize the asymmetric synthesis of pharmaceuticals called chiral macrocyclic dilithium(I) salt. It overcomes the lack of ...
Analytical Chemistry
Jan 11, 2024
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1
MYC is the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering hope for a new era of treatments.
Biochemistry
Jan 11, 2024
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468
Single-use plastics are a major environmental concern, but now, rather than being disposed of as garbage, used plastic bags from the grocery store could be utilized to carry out a reaction that can detoxify hazardous chemicals.
Materials Science
Dec 27, 2023
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63
Lassa virus (LASV) is the pathogen that causes Lassa hemorrhagic fever, a disease endemic to West Africa, which causes approximately 5,000 deaths each year. At the CSSB Centre for Structural Systems Biology, the Uetrecht ...
Biochemistry
Dec 21, 2023
0
70
When Senior Scientist Jonathan Grimm came to Janelia 13 years ago, he didn't know much about fluorescence or fluorescent dyes. But as an organic chemist who had been working in drug discovery at Merck, he certainly knew a ...
Analytical Chemistry
Dec 8, 2023
0
20
A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved ...
Ocean acidification, mammal respiration, and aerosol formation all depend on chemistry that occurs at air-water interfaces. In new research, scientists from the Department of Energy's Lawrence Berkeley National Laboratory ...
Biochemistry
Dec 4, 2023
0
61
Basic oxide catalysts contain oxygen ions with unpaired electrons that can be shared with other species to facilitate a chemical reaction. These catalysts are widely used in the synthesis of chemicals, pharmaceuticals, and ...
Analytical Chemistry
Nov 30, 2023
0
13
The idea of irreversible inhibitors adhering permanently to a target protein has gained increasing attention for application in potential drug development. However, one of many hurdles is the possibility of protein mutations ...
Biochemistry
Nov 29, 2023
0
20
