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Biochemistry news

Chemists develop new method to synthesize chiral bridged polycyclic compounds for drug discovery
A Hong Kong University of Science and Technology (HKUST) research team has developed a catalytic enantioselective type II [5 + 2] cycloaddition method to address the challenges of synthesizing chiral bridged polycyclic ...
Biochemistry
18 hours ago
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Chemical reaction linking sugar metabolism and cellular protection discovered
When we consume foods containing sugar and starch, they are converted into energy in the body's cells through a process called glycolysis.
Biochemistry
18 hours ago
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Terahertz calorimetry captures thermodynamics of protein and water interactions at picosecond resolution
Researchers from Ruhr University Bochum, Germany, have developed a new method that allows them to visualize the contribution of the interaction between water and proteins for the first time with extreme temporal resolution. ...
Biochemistry
Jun 3, 2025
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Sugar-based sensors offer rapid, low-cost detection of snake venom
Researchers at The University of Warwick have published the first example of a synthetic sugar detection test for snake venom, offering a new route to rapid diagnosis and better antivenoms.
Biochemistry
Jun 2, 2025
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Harnessing the power of 'click chemistry' to make biomolecular labeling safe for live cells
One of the longstanding challenges in chemical biology has been finding ways to directly observe biological processes at work inside living cells without disturbing the action. In order to unlock new therapies and better ...
Biochemistry
May 29, 2025
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Kinetic coupling: Structure and dynamics of biochemical networks linked through new concept
A new concept of kinetic modules in biochemical networks could revolutionize the understanding of how these networks function. Scientists from the University of Potsdam and the Max Planck Institute of Molecular Plant Physiology ...
Biochemistry
May 29, 2025
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Artificial cell-like structures mimic self-reproduction and release polymeric spores
Life on Earth possesses an exceptional ability to self-reproduce, which, even on a simple cellular level, is driven by complex biochemistry. But can self-reproduction exist in a biochemistry-free environment?

Re-inventing the cheese wheel: Researchers work on optimizing plant-based dairy
Chemical engineers at UNSW Sydney have created a plant-based cheese that melts, stretches and browns under the grill like the real thing, paving the way for more realistic dairy and meat alternatives that blend plant proteins ...
Biochemistry
May 29, 2025
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Don't like the taste of fava beans? Research helps improve flavor
Fava beans are a promising plant-based protein source, but many find their flavor unpleasant. A study conducted at the University of Helsinki investigated the root causes of the flavor issues to help develop solutions for ...
Biochemistry
May 28, 2025
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How the fight-or-flight response resets on a molecular level
Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allow the body to react swiftly to stress or starvation. Critical to this "fight-or-flight" or stress ...
Biochemistry
May 28, 2025
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Early Earth chemistry: Triplet RNA building blocks and freeze-thaw cycles enable self-replication in water
Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth—a key process in the origin of life.
Biochemistry
May 28, 2025
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Cryo-em freezes the funk: Scientists visualize a pungent protein
They say a picture is worth a thousand words. But it takes millions of pictures to understand the intricate chemistry of an enzyme that helps break down sulfur, commonly found in fruits, vegetables, alcohol and gasoline, ...
Biochemistry
May 27, 2025
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Less bitter, just as satiating—study on pea protein hydrolyzates delivers surprising findings
A study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows that less bitter-tasting pea protein hydrolyzates can induce just as strong satiety signals in stomach cells as their more ...
Biochemistry
May 27, 2025
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Copper death-inhibiting compounds isolated from eucalyptus fruits show promise for cancer therapy
Researchers have isolated two novel bis-β-triketone hybrids, Corymbinols A (1) and B (2a/2b), from the fruits of Corymbia citriodora. Corymbinol A demonstrated a 31% inhibition of cuproptosis in HepG2 cells at a concentration ...
Biochemistry
May 27, 2025
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Assembly instructions for enzymes: Universal rules can help to design an optimal enzyme from scratch
In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) have now derived universal rules to enable the de novo ...
Biochemistry
May 26, 2025
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A dental floss that can measure stress
Chronic stress can lead to increased blood pressure and cardiovascular disease, decreased immune function, depression, and anxiety. Unfortunately, the tools we use to monitor stress are often imprecise or expensive, relying ...
Biochemistry
May 26, 2025
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Two-step method dismantles bacterial biofilms and prevents regrowth for months
Most people have encountered the black, gray, or pink stains of bacterial biofilms built up on the bathroom tiles or kitchen sink. Even with vigorous scrubbing and strong cleaning chemicals, this grime can be difficult to ...
Biochemistry
May 22, 2025
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Atom-swapping method successfully applied to complex organic structures—new possibilities for drug design
Skeletal editing is a modern approach to chemical synthesis. By making precise alterations at the atomic level, researchers are able to directly convert existing drug scaffolds into new, biologically relevant compounds.
Biochemistry
May 22, 2025
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Redox-switchable dyes offer tunable fluorescence for advanced bioimaging and optical applications
Fluorescent molecules that absorb and emit light in the near-infrared (NIR) and short-wave infrared (SWIR) regions have significant potential for various applications. These molecules can serve as markers for imaging biological ...
Biochemistry
May 22, 2025
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One-pot protein screening accelerates bioscience and drug discovery
Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic candidates, like antibodies that bind to and fight the SARS-CoV-2 virus, can be explored and simulated ...
Biochemistry
May 22, 2025
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Chemists discover simple way to build bigger molecules, one carbon at a time

'String breaking' observed in 2D quantum simulator
