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Molecular & Computational biology news
Data mining uncovers treasure-trove of previously 'untouchable' proteins for drug development
Molecular glues, tiny molecules that connect one protein to another, are promising targets for pharmaceutical research. By linking a disease-related protein to one that triggers a cell's demolition and recycling pathways, ...
Cutting to the core of how 3D structure shapes gene activity
In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how stretches of DNA form genes, ...
Biotechnology
Jul 11, 2025
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How the genome defends itself against internal enemies
An international research team has deciphered a mechanism of the evolutionary arms race in human cells. The findings provide insights into how mobile elements in DNA hijack cellular functions—and how cells can defend themselves ...
Molecular & Computational biology
Jul 11, 2025
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Plant phototropism regulated by acetylation–phosphorylation cross-talk, study finds
Plant phototropism—directional growth in response to light—serves as a key adaptive mechanism, optimizing photosynthesis and development. Central to this process is phototropin 1 (phot1), a primary blue light photoreceptor ...
Plants & Animals
Jul 11, 2025
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New AI tool models protein dynamics, aiding drug discovery and protein research
A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science. The study introduces BioEmu, a generative deep learning system that emulates the equilibrium behavior ...
Biotechnology
Jul 11, 2025
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Novel tool to study stress-dependent subcellular protein localization changes
Using a high-throughput fluorescence microscopy system and machine learning algorithms, oxidative stress-related changes in protein localization have been mapped by researchers from Japan. Furthermore, a comprehensive database ...
Cell & Microbiology
Jul 11, 2025
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Study details rare live-birth strategy in cricket-hunting parasitic fly
A study published in the Annals of the Entomological Society of America, offers the most detailed view to date of how this unusual fly develops and gives live birth—a rare phenomenon among flies.
Plants & Animals
Jul 11, 2025
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Scientist's cat, again, helps discover new virus
Pepper, the pet cat who made headlines last year for his role in the discovery of the first jeilongvirus found in the U.S., is at it again. This time, his hunting prowess has contributed to the identification of a new strain ...
Molecular & Computational biology
Jul 10, 2025
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217
Illuminated sugars show how microbes eat the ocean's carbon
A team of chemists, microbiologists and ecologists has designed a molecular probe (a molecule designed to detect proteins or DNA inside an organism, for example) that lights up when a sugar is consumed.
Molecular & Computational biology
Jul 10, 2025
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Molecular biologists identify multifunctional virus-sensing protein
As part of a person's first line of defense against viruses and other microbes that cause illness and disease, a whole network of proteins and other molecules detect and respond to intruders, which they do in part by sensing ...
Cell & Microbiology
Jul 10, 2025
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Fundamental role of the membrane structure of mitochondria identified
Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the metabolism of the cell, they also play a key role in the integration of signals into the cell, which are ...
Molecular & Computational biology
Jul 10, 2025
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Scientists develop novel recording tool to monitor protein kinase activities in living cells
The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular processes. Scientists at the Max Planck Institute for Medical Research in Heidelberg have now developed ...
Biotechnology
Jul 10, 2025
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The RNA revolution: How our understanding of life's blueprint is being rewritten
For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained classic Mendelian ...
New tool maps hidden roles and risks in ecosystems
Do you think you know which species are most vulnerable in an ecosystem? A novel analytical method developed by Italian physicists at the Complexity Science Hub (CSH) suggests there's more to discover. In their recent study, ...
Ecology
Jul 10, 2025
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Genetic 'barcode' discovery cracks the code of centromeres, the genome's most mysterious regions
When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there's a whole lot of DNA beyond genes that we are just starting to understand. One such mysterious ...
Genomic study reveals deep roots of human survival and adaptation in Himalayas
A new genomic study reveals how human populations adapted, survived, and diversified in the Himalayas, one of the most extreme and challenging environments on Earth.
Evolution
Jul 10, 2025
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Chemicals from turmeric and rhubarb could help fight antibiotic-resistant bacteria lurking in wastewater
When people take antibiotics, some of the dose is excreted with urine and feces and ends up in our wastewater. The presence of this low dose of antibiotic creates an opportunity for resistant bacteria to evolve.
Cell & Microbiology
Jul 10, 2025
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109
Thirty years of research shows increased resistance in fungi
Fungi are increasingly resistant to antifungals, and the variation in resistance has significantly increased. This is evident from the analysis of more than 12,000 lung samples collected over 30 years in Dutch hospitals. ...
Cell & Microbiology
Jul 9, 2025
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Why some genes are more error-prone: Scientists uncover hidden rule in DNA transcription
Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological Physics at Rice University ...
Molecular & Computational biology
Jul 9, 2025
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A molecular switch packs DNA on time for cell division
If measured from beginning to end, the DNA in our cells is too long to fit into the cell's nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the genetic information ...
Molecular & Computational biology
Jul 9, 2025
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Chickadees recall places by simply looking from afar
New method removes mysterious organelles from stem cells and embryos to reveal their roles
