New method could cut waste from drug production
Scientists have developed a sustainable new way of making complex molecules, which could greatly reduce waste produced during drug manufacturing, a study suggests.
Scientists have developed a sustainable new way of making complex molecules, which could greatly reduce waste produced during drug manufacturing, a study suggests.
Analytical Chemistry
Apr 24, 2024
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The corn leafhopper Dalbulus maidis has become a serious problem for farmers. This tiny insect is now widely distributed in the Americas, from the south of the United States to the north of Argentina. In Brazil, it uses only ...
Ecology
Mar 6, 2024
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26
It's been a long, eight-day leap week, and this weekend, I'm spending my free time working on the manuscript for my style guide for science writers, "How to Effectively Split an Infinitive."
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Biochemistry
Jan 22, 2024
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It is common knowledge that humans have a big effect on the world and their natural environment. However, what may be less well-known is that humans can also induce earthquakes. Industrial activities such as geothermal energy ...
Earth Sciences
Jan 15, 2024
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114
A research group led by Prof. Wang Hui from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences has introduced a metal-free nanozyme based on graphene quantum dots (GQDs) for highly efficient ...
Bio & Medicine
Jan 10, 2024
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International research led by the Translational Synthetic Biology Laboratory of the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University has succeeded in efficiently engineering Cutibacterium acnes, ...
Cell & Microbiology
Jan 9, 2024
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Brazilian snake and spider venoms continue to be a source of new discoveries with biotechnological potential. Two recently published studies show how this is possible even in relatively well-studied species such as the lancehead ...
Biotechnology
Jan 4, 2024
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285
Bisphosphonate (BP) drugs are a common treatment strategy to combat calcium-related metabolic disorders, osteoporosis being the most widely known one. These drugs offer several benefits but are plagued by side-effects. One ...
Analytical Chemistry
Dec 11, 2023
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ETH Zurich researchers have shown for the first time that microvehicles can be steered through blood vessels in the brains of mice using ultrasound. They hope that this will eventually lead to treatments capable of delivering ...
Bio & Medicine
Dec 7, 2023
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27
In medicine, an adverse effect is a harmful and undesired effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect, and may result from an unsuitable or incorrect dosage or procedure, which could be due to medical error. Adverse effects are sometimes referred to as "iatrogenic" because they are generated by a physician/treatment. Some adverse effects only occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Adverse effects may cause medical complications of a disease or procedure and negatively affect its prognosis. They may also lead to non-compliance with a treatment regimen.
The harmful outcome is usually indicated by some result such as morbidity, mortality, alteration in body weight, levels of enzymes, loss of function, or as a pathological change detected at the microscopic, macroscopic or physiological level. It may also be indicated by symptoms reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals, foods, or procedures, such as drug interactions.
In clinical trials, a distinction is made between adverse events (AEs) and serious adverse events (SAEs). Generally, any event which causes death, permanent damage, birth defects, or requires hospitalization is considered an SAE. The results of these trials are often included in the labeling of the medication to provide information both for patients and the prescribing physicians.
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