Solving a crucial bottleneck in drug discovery

Many existing antibiotics were derived from soil bacteria, which naturally produce these toxins to ward off competitors. But efforts to draw more therapeutics from the ground have hit a snag. Most species cannot be grown ...

Dual-plasmid editing system improves DNA digital storage potential

DNA-based information is a new interdisciplinary field linking information technology and biotechnology. The field hopes to meet the enormous need for long-term data storage by using DNA as an information storage medium. ...

Video: 'Mapping' the body with single-cell RNA sequencing

While nearly every cell in the body contains identical genetic instructions packaged in DNA, there is flexibility on how that genetic information is expressed and in turn translated through RNA to create proteins, the building ...

New tool offers ways to improve CRISPR gene-editing method

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing technologies frequently ...

Research advances emerging DNA sequencing technology

Nanopore technology shows promise for making it possible to develop small, portable, inexpensive devices that can sequence DNA in real time. One of the challenges, however, has been to make the technology more accurate.

A new way to visualize mountains of biological data

Studying genetic material on a cellular level, such as single-cell RNA-sequencing, can provide scientists with a detailed, high-resolution view of biological processes at work. This level of detail helps scientists determine ...

Ocean research in a time of COVID-19

The COVID-19 pandemic has made it especially challenging for marine scientists to make observations and carry out experiments at sea. Research cruises have been cut back or canceled because it is difficult to keep a safe ...

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