Sepsis study to power new antibiotic discoveries
University of Queensland researchers have led a national study on the four main bacteria that cause sepsis, providing new targets for developing antibiotics.
University of Queensland researchers have led a national study on the four main bacteria that cause sepsis, providing new targets for developing antibiotics.
Cell & Microbiology
Mar 28, 2023
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Every year, almost 7 million potentially serious bacterial infections are estimated to occur in newborns, resulting in more than 550,000 annual neonatal deaths. Most of these infections and deaths happen in LMICs, where often ...
Cell & Microbiology
Aug 4, 2022
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39
The two key molecules that interact to drive fungal sepsis and meningitis are IP7—a molecule essential for fungal cell metabolism, and the protein Pho81—which regulates intake of the essential nutrient, phosphate.
Cell & Microbiology
Oct 21, 2020
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EPFL researchers have developed a highly sensitive and portable optical biosensor that stands to accelerate the diagnosis of fatal conditions like sepsis. It could be used by ambulances and hospitals to improve the triage ...
Bio & Medicine
Jan 23, 2020
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Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body's extreme reaction to infection.
Bio & Medicine
Jan 6, 2020
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A deep learning approach originally designed to teach computers how to play video games better than humans could aid in developing personalized medical treatment for sepsis, a disease that causes about 300,000 deaths per ...
Machine learning & AI
Dec 19, 2018
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A team of researchers at the University of California San Diego has developed macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis. These macrophage nanosponges, ...
Bio & Medicine
Jan 4, 2018
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A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood.
Analytical Chemistry
Jul 3, 2017
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560
(Phys.org) —Scientists have discovered a natural temperature sensor in a type of bacteria that causes meningitis and blood poisoning. The sensor allows the bacteria to evade the body's immune response, leading to life-threatening ...
Cell & Microbiology
Sep 26, 2013
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In Africa hundreds of rhinos are shot or immobilised by poachers every year to supply ground up horn for the Asian medicine market. It is reputed to make men virile and treat anything from stomach ache to cancer - all just ...
Ecology
Jun 21, 2013
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Sepsis is a serious medical condition characterized by a whole-body inflammatory state (called a systemic inflammatory response syndrome or SIRS) and the presence of a known or suspected infection. The body may develop this inflammatory response to microbes in the blood, urine, lungs, skin, or other tissues. An incorrect layman's term for sepsis is blood poisoning, more aptly applied to Septicemia, below.
Septicemia (also septicæmia [sep⋅ti⋅cæ⋅mi⋅a], or erroneously Septasemia and Septisema) is a related but deprecated (formerly sanctioned medical) term referring to the presence of pathogenic organisms in the blood-stream, leading to sepsis. The term has not been sharply defined. It has been inconsistently used in the past by medical professionals, for example as a synonym of bacteremia, causing some confusion. The present medical consensus is therefore that the term[which?] is problematic and should be avoided.
Sepsis is usually treated in the intensive care unit with intravenous fluids and antibiotics. If fluid replacement is insufficient to maintain blood pressure, specific vasopressor drugs can be used. Artificial ventilation and dialysis may be needed to support the function of the lungs and kidneys, respectively. To guide therapy, a central venous catheter and an arterial catheter may be placed. Sepsis patients require preventive measures for deep vein thrombosis, stress ulcers and pressure ulcers, unless other conditions prevent this. Some patients might benefit from tight control of blood sugar levels with insulin (targeting stress hyperglycemia), low-dose corticosteroids or activated drotrecogin alfa (recombinant protein C).
This text uses material from Wikipedia, licensed under CC BY-SA