Imagine a dark room packed full of furniture. Now imagine moving through it to get to the other side, using only your toe tips for guidance. While it may seem challenging (or unspeakably tedious) to us, this is a task that ...
Cell & Microbiology
Sep 13, 2023
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14
A single human cell teems with as many 100,000 different proteins. Actin is one of the most abundant and essential of them all. This protein forms into filaments that help make up the skeleton of cells, giving them shape. ...
Cell & Microbiology
Jul 20, 2023
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112
Actin filaments—protein structures critical to living movement from single cells to animals—have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ...
Cell & Microbiology
Jun 8, 2023
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133
In a study published in Science Advances, Dr. Cong Yao's team from the Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences, reported a complete ...
Cell & Microbiology
Mar 30, 2023
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3
A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.
Biochemistry
Feb 16, 2023
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24
Bacterial pathogens like Salmonella, Shigella, Listeria and many others exploit the protein skeleton of the cells they infect in order to spread throughout the host. However, how is this so-called cytoskeleton of host cells ...
Cell & Microbiology
Dec 15, 2022
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51
A recent study led by Assistant Professor of Gerontology Ryo Sanabria has identified a key protein that helps regulate the actin cytoskeleton, a scaffold of proteins within cells that makes their proper structure and function ...
Cell & Microbiology
Dec 12, 2022
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5
Inside the leading edge of a crawling cell, intricate networks of rod-like actin filaments extend toward the cell membrane at various angles, lengthening protein by protein. Upon impact, the crisscrossing rods glance off ...
Biochemistry
Oct 26, 2022
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35
Protein structures are typically determined by studying them in their purified form, outside the busy inner workings of the cell, and because of this, their biological relevance is often called into question. In a new study ...
Biotechnology
Jun 9, 2022
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39
A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.
Cell & Microbiology
May 19, 2022
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43
