Related topics: brain · nerve cells · brain cells · cells · protein

New technique developed for targeted protein degradation

A new study published in Nature Communications from researchers at Karolinska Institutet solves a long-standing problem by establishing a system that allows site-specific protein degradation within mitochondria, the cellular ...

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Neurodegenerative disease

Neurodegenerative disease (Greek νέυρο-, néuro-, "nerval" and Latin dēgenerāre, "to decline" or "to worsen") is a condition in which cells of the brain and spinal cord are lost. The brain and spinal cord are composed of neurons that do different functions such as controlling movements, processing sensory information, and making decisions. Cells of the brain and spinal cord are not readily regenerated en masse, so excessive damage can be devastating. Neurodegenerative diseases result from deterioration of neurons or their myelin sheath which over time will lead to dysfunction and disabilities resulting from this.

Some sources limit the term "degenerative" to conditions primarily affecting gray matter that are not associated with a obvious inciting event.

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