A recent study from the University of Eastern Finland shows that genetic variation determines chromatin accessibility and the binding of transcription factors. Chromatin consists of DNA and proteins attached to it. The density ...
Molecular & Computational biology
Jan 22, 2024
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5
(Phys.org)—A trio of researchers affiliated with several institutions in Belgium has developed a bioinformatics tool that allows for comparing protein-coding genes of 36 inbred mouse strains to the C57BL/6J strain. In their ...
Mouse models are extensively used in pharmaceutical and medical research, and it is known that the communities of microbes in their intestine can have a significant impact on the research output. However, there is still insufficient ...
Cell & Microbiology
Aug 12, 2016
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470
Jackson Laboratory researchers have shown that using an electric current to deliver the CRISPR/Cas9 system, in order to engineer genetic changes in laboratory mice, is highly efficient and significantly improves the system's ...
Biotechnology
Jun 8, 2015
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64
Laboratory mice are one of the most common animal models used in biological and medical research. Thousands of laboratory mouse strains are produced by artificial selection – the process by which humans breed animals over ...
Plants & Animals
Aug 5, 2014
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0
Today we are constantly online and integrated in a virtual existence. Wii and other game modules make it possible to engage the entire body when playing, and soon Google Glasses and similar products will open up a whole new ...
Hi Tech & Innovation
May 7, 2014
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0
Over the last few decades, scientists have drawn upon a powerful arsenal of biotechnology techniques to establish a wide variety of genetically engineered mouse strains. These animals represent invaluable resources for studying ...
Biotechnology
Aug 16, 2013
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0
(Phys.org) —Jonathan Tang had a problem. A graduate student studying neural circuitry in the retina, he wanted to do more than identify fluorescent cells that send signals to the brain. He sought to understand how these ...
Biotechnology
Aug 16, 2013
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0
(Phys.org)—In the November issue of the journal Molecular Ecology, a U.S. and Brazilian research team reported evidence of novel and hybrid strains of a lethal fungus that has decimated amphibian populations worldwide. ...
Plants & Animals
Nov 20, 2012
1
0
Differences in the levels of two key metabolic enzymes may explain why some people are more susceptible to liver damage, according to a study in the October 17 issue of the Journal of Cell Biology.
Cell & Microbiology
Oct 17, 2011
0
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