Artificial lipid bilayer vesicle liposomes, also called proteoliposomes, are specialized systems capable of incorporating various molecules, such as chemicals and drugs. Their unique properties make them ideal carriers for ...
Biochemistry
Jun 28, 2023
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29
A new study by the University of Barcelona has analyzed the viability of a new nanomolecule as drug delivery vehicle. The results, published in the journal Colloids and Surfaces B: Biointerfaces, show that liposomes designed ...
Bio & Medicine
Jan 10, 2023
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9
A biocompatible polymer could help deliver vaccines and drugs with reduced risk of the rare dangerous adverse reaction called anaphylaxis. Researchers at the National Institute of Advanced Industrial Science and Technology ...
Biochemistry
Dec 9, 2022
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20
Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% ...
Bio & Medicine
Oct 31, 2022
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5
Liposomes may be the unsung heroes of the COVID-19 pandemic. Without the protection of these microscopic vesicles, the delicate strands of messenger RNA (mRNA) that lie at the heart of the Pfizer and Moderna COVID-19 vaccines ...
Bio & Medicine
Nov 15, 2021
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134
Scientists have worked out how to best get DNA to communicate with membranes in our body, paving the way for the creation of 'mini biological computers' in droplets that have potential uses in biosensing and mRNA vaccines.
Bio & Medicine
Oct 15, 2021
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128
Dmitri Simberg, Ph.D., associate professor in the University of Colorado Skaggs School of Pharmacy, has released the results of a study of the effectiveness of different types of fluorescent labels used to monitor the accumulation ...
Bio & Medicine
Jul 8, 2021
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14
Since the introduction on the market in 1995 of Doxil, pegylated liposomal doxorubicin, liposomes have become one of the most clinically established drug delivery systems in nanomedicine. Among different liposomal formulations, ...
Molecular & Computational biology
Jun 1, 2021
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4
Light-activated liposomes could help to deliver CRISPR gene therapy—and the method could prove safer and more direct than current methods.
Biotechnology
Nov 12, 2020
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398
Alzheimer's disease (AD) is one of the biggest global public health challenges. However, the pathogenesis of AD is still unclear.
Biochemistry
Jul 9, 2020
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9
Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease. Liposomes can be prepared by disrupting biological membranes, for example by sonication.
Liposomes can be composed of naturally derived phospholipids with mixed lipid chains (like egg phosphatidylethanolamine) or other surfactants. Liposomes should not be confused with micelles and reverse micelles composed of monolayers.
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