The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.
Cell & Microbiology
Jul 24, 2023
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5
A new study published in Cell Chemical Biology describes an alternative approach to treat diabetes by identifying drugs directly increasing the number of incretin-expressing cells. The work results from researchers at Karolinska ...
Biochemistry
Aug 23, 2022
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39
A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable ...
Biochemistry
Mar 25, 2022
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24
In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. Their study, involving the roundworm C. elegans, ...
Cell & Microbiology
Feb 25, 2020
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203
Scientists from the University of Bristol have designed a new synthetic glucose binding molecule platform that brings us one step closer to the development of the world's first glucose-responsive insulin which, say researchers, ...
Biochemistry
Nov 19, 2018
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552
New research from the University of Copenhagen points to an entirely new approach for designing insulin-based pharmaceuticals. The approach could open the door for more personalized medications with fewer side effects for ...
Biochemistry
Feb 18, 2016
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26
Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the question of how this key hormone binds to its target cells ...
Biochemistry
Aug 4, 2014
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0
The body's cell machinery often attaches sugar chains onto proteins to create molecules that play a crucial role in everything from protective immunity to structural stability. However, distinguishing between the different ...
Analytical Chemistry
Nov 30, 2012
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0
Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even ...
Biochemistry
Nov 23, 2011
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0
(PhysOrg.com) -- German researchers have discovered a new mechanism that leads to the development of type 2 diabetes in obesity.
Cell & Microbiology
Mar 31, 2011
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