The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...
Bio & Medicine
Apr 3, 2024
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18
RNA (ribonucleic acid), which is made up of ribonucleotides, is a molecule found in all living organisms. RNA is thought to have probably preceded DNA in primordial life billions of years ago. RNA was eventually replaced ...
Molecular & Computational biology
Nov 27, 2023
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1
Mesenchymal stem cells (MSCs) have great potential for the treatment of various immune diseases due to their unique immunomodulatory properties. However, MSCs exposed to the harsh inflammatory environment of damaged tissue ...
Cell & Microbiology
Nov 27, 2023
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1
A new study, published in Nature Nanotechnology, may offer a strategy that mitigates negative side effects associated with intravenous injection of nanoparticles commonly used in medicine.
Bio & Medicine
Oct 5, 2023
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7
Toxoplasma gondii—otherwise known as Toxo—is a parasite that infects one fourth of the world's human population. While Toxo remains alive within most of its hosts, the active acute forms of the parasite are quickly suppressed ...
Cell & Microbiology
Apr 21, 2023
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83
Have a cough, sore throat and congestion? Any number of respiratory viruses could be responsible. Conventional tests can identify certain likely culprits by relying on chemical reactions, but some researchers want to swap ...
Analytical Chemistry
Mar 28, 2023
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34
Scientists have long known that wild seabirds ingest bits of plastic pollution as they feed, but a study Monday shows the tiny particles don't just clog or transit the stomach but can subvert its complex mix of good and bad ...
Ecology
Mar 27, 2023
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51
Specific fatty acid-sugar molecules allow leprosy bacteria, among others, to hide from our immune system. How exactly is not entirely clear. Hessel van Dijk, who received his Ph.D. on October 13, replicated the molecules, ...
Cell & Microbiology
Oct 14, 2022
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1
In higher organisms, detection of DNA in the cytoplasm triggers an immune reaction. The enzyme that senses "misplaced" DNA is also found in the nucleus, but nuclear DNA has no such effect. LMU researchers now report why that ...
Molecular & Computational biology
Sep 11, 2020
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32
The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable "hinges." The shape ...
Biochemistry
Apr 24, 2020
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33
