How hydrophobicity shapes protein assemblies

Through a nuanced balance of electrical and hydrophobic forces, biological molecules self-assemble into the large functional structures that maintain life's vital functions. Understanding how proteins self-assemble requires ...

Deep learning for new protein design

The key to understanding proteins—such as those that govern cancer, COVID-19, and other diseases—is quite simple: Identify their chemical structure and find which other proteins can bind to them. But there's a catch.

Biomaterials for kidney organoid–based regenerative therapy

With the discovery of synthetic stem cells, better known as induced pluripotent stem cells, the field or regenerative medicine has been revolutionized. These synthetic stem cells are created by reprogramming adult cells from ...

How cells control their borders

Bacteria, fungi, and yeast are very good at excreting useful substances such as weak acids. One way in which they do this is through passive diffusion of molecules across the cell membrane. At the same time, cells need to ...

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