Role of morphogens in tissue patterning in heart development

Morphogens are molecules that travel from cell to cell in order to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult during tissue repair. However, ...

New tool to accelerate drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones—or chemical messengers—bind to cell membrane receptors to fine tune how the cell behaves. Once ...

Organoids produce embryonic heart

There was a time when the idea of growing organs in the lab was the stuff of science fiction. Today, stem cell biology and tissue engineering are turning fiction into reality with the advent of organoids: tiny lab-grown tissues ...

Understanding congenital heart defects, one chicken at a time

Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...

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