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Research provides insight into constructing gene regulatory networks

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes. ...

Battling persistence in tuberculosis bacteria

Researchers at the Indian Institute of Science (IISc), in collaboration with NCBS and InStem, have uncovered an important mechanism that allows the tuberculosis (TB) bacterium to persist in the human host for decades. They ...

Machine learning method improves cell identity understanding

When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs. Discovering these patterns improves our understanding of cells—which has implications ...

Self-assembling proteins can store cellular 'memories'

As cells perform their everyday functions, they turn on a variety of genes and cellular pathways. MIT engineers have now coaxed cells to inscribe the history of these events in a long protein chain that can be imaged using ...

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